Eleven years ago, Jan and Garet Hil’s 10-year-old daughter experienced sudden kidney failure. When no immediate family members proved to have compatible kidneys they could donate, the Hils had to enter the unfamiliar territory of donor kidney matchmaking. It was a harrowing experience. A kidney-swap exchange occurs when someone wants to donate a kidney to a loved one but cannot because they aren’t the right fit.
They agree to swap with someone else as long as their loved one receives a match somewhere down the chain. When the Hil’s daughter needed a kidney, the kidney-swap landscape was a sea of isolated islands: disparate programs that lacked connection to a central database.
For the Hils, this resulted in a process that involved long painful weeks waiting for potential match results as their doctors — and those up and down the chain — reviewed CT donor kidney images sent through snail mail.
Sometimes they never even heard back from the exchange programs. Finally, a cousin proved to be a match, and the little girl received her new kidney in July 2007.
Frustrated by their experience, the Hils decided to transform the industry. They launched the nonprofit National Kidney Registry (NKR) in 2007 in an effort to increase the quality, speed and number of living donor transplants in the world.
Since its inception, the NKR has implemented a number of key innovations — such as GPS tracking for shipping organs, specialised coding to ensure antibody matches, and enabling remote donation so donor and recipient surgeries don’t have to take place in the same city. The NKR has facilitated 2,667 transplants so far.
It’s been a welcome change. Chronic kidney disease, often caused by diabetes and high blood pressure, affects approximately 14 percent of the general population and kills more people than breast or prostate cancer.
According to the National Kidney Foundation, kidney transplant patients live longer than those on dialysis (an IV treatment that flushes waste, chemicals and excess fluids from the blood, just as a healthy kidney would do).
Successful kidney donations depend on compatible blood types, antibodies, organ sizes and vascularity. The recipient’s doctors determine this compatibility by examining CT images of the donor kidney.
But despite NKR’s success in connecting recipients with potential donors, the fact that doctors were still exchanging CT images of kidneys on CDs via mail delayed the matching process.
Sometimes it would take up to 10 days to conduct an imaging scan, transfer the image to a CD, mail it to the recipient’s doctors, and wait to see if the donor was ruled in — or out, in which case the painstaking process would have to start all over again.
So, in 2016, the NKR partnered with GE Healthcare and VasoHealthcare IT, an imaging solutions consultant and provider, to help reduce the image-review process time from 10 days to 10 minutes by digitising the image exchange and review.
“Physicians have to really look at these images to determine if there’s a potential match,” says GE Healthcare’s Matt Atwood. “If not, it’s important to get these participants back into the matching process pool as soon as possible.”
The system runs on GE Healthcare’s Centricity Universal Viewer Zero Footprint (ZFP) system, which provides the backbone for image access, archiving and visualisation over the cloud.
Although it doesn’t use machine learning, the system is an excellent example of “intelligent” software — it utilises a proprietary, adaptive streaming technology that adjusts to the users’ network bandwidth and device, optimising quality and speed of display.
This way, doctors can use the most common web browser or mobile device to instantly and clearly access donor images from other NKR member centers around the country.
“Think of our Zero Footprint technology as a medical imaging repository in cloud storage,” Atwood says. “Hospitals connected with NKR can upload their images to a safe and accessible environment where they are stored. Physicians view them here and share information back and forth in near real time.”
In addition to helping critically ill patients find matches sooner, this new solution has also saved kidney-match coordinators nearly two months of time annually in operational tasks, allowing them to focus instead on patient cases.
“As our donor pool grows and our volume grows, we don’t want to lose any momentum,” says Joe Sinacore, NKR’s director of education and development. “We need to remain focused on getting people matched and off dialysis as soon as possible, and the GE Healthcare solution enables us to do just that.”
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Image credit: GE Healthcare.