A team of Massachusetts General Hospital (MGH) investigators has developed an antibiotic-releasing polymer that may greatly simplify the treatment of prosthetic joint infection. In their recent report published in Nature Biomedical Engineering, the researchers describe how implants made from this material successfully eliminated two types of prosthetic infection in animal models.

  A multi-institutional team based at Massachusetts General Hospital (MGH) has discovered how a potential treatment strategy for Huntington disease (HD) produces its effects, verified its action in human cells and identified a previously unknown deficit in neural stem cells from patients with HD.

A procedure developed at Massachusetts General Hospital (MGH) may revolutionise the culturing of adult stem cells. In their report that has been published online prior to its appearance in Cell Stem Cell, the team describes generating and expanding airway stem cells from the sorts of tissue samples collected during routine treatment of lung disorders. The overall approach appears applicable to several other tissue types, including skin and the li...

A team of researchers from Massachusetts General Hospital (MGH) and the Rowland Institute at Harvard University have used a specialised nanoprobe developed by the Harvard/Rowland investigators to directly measure levels of key proteins within living, cultured cells. As described in the journal Nano Letters, the investigators used the device to track levels of the Alzheimer's-disease-associated proteins amyloid-beta (A-beta) and tau in neurons and...