Treatment

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Bio-based mesh can aid hernia treatment

Bio-based mesh can aid hernia treatment
A novel bio-based scaffold promises significantly better clinical performance in hernia operations. Mesh repair of hernias is now standard in most countries. Typically, a non-degradable polymeric mesh is placed at the site of organ protrusion to act as a scaffold for reinforcing tissue growth. However, customarily used non-degradable polymers are often associated with a high rate of foreign body reaction and hernia recurrence. In addition, current processing methods employ technologies that are associated with environmental risks.
21st June 2016

Procedure allows long-term culturing of adult stem cells

A procedure developed at Massachusetts General Hospital (MGH) may revolutionise the culturing of adult stem cells. In their report that has been published online prior to its appearance in Cell Stem Cell, the team describes generating and expanding airway stem cells from the sorts of tissue samples collected during routine treatment of lung disorders. The overall approach appears applicable to several other tissue types, including skin and the linings of the gastrointestinal and reproductive tracts.
17th June 2016

Microfluidic technology assists infertile couples

Microfluidic technology assists infertile couples
Of the millions of sperm that enter the vagina, only about 10 or so make it to the oocyte or egg, demonstrating how rigorous the natural sperm selection process really is. So how is it possible to select only the best sperm for assisted reproductive technologies such as in vitro fertilisation? That's what a researcher at Florida Atlantic University is aiming to do with his microfluidic technology for reproductive medicine.
16th June 2016


Method enables development of next-gen medicines

Scientists at The Scripps Research Institute (TSRI) have developed a powerful new method for finding drug candidates that bind to specific proteins. The method, reported in this week's issue of Nature, is a significant advance because it can be applied to a large set of proteins at once, even to the thousands of distinct proteins directly in their native cellular environment.
16th June 2016

Exoskeleton helps child with spinal muscular atrophy

Exoskeleton helps child with spinal muscular atrophy
Researchers have introduced the world's first infant exoskeleton designed to help children with spinal muscular atrophy, a degenerative illness. Weighing 12 kg, the apparatus is made of aluminium and titanium, and is designed to help patients walk—in some cases, for the first time. It can also be used in hospital-based physiotherapy to prevent secondary effects associated with the loss of mobility associated with spinal muscular atrophy.
9th June 2016

Approaches to fighting antibiotic-resistant bacteria

Approaches to fighting antibiotic-resistant bacteria
With the recent finding in Pennsylvania of a hospital patient with an E.coli infection that resists colistin, an antibiotic used as the last line of defense against multi-drug resistant bacteria, the scientific and medical communities continue to search for answers to the menace of superbugs. While common antibiotics were able to treat the patient, the major concern is the spread of an antibiotic resistance factor previously unseen in the United States.
8th June 2016

Breath analysis aims to reduce unnecessary antibiotic prescriptions

The overuse of antibiotics gives harmful bacteria the opportunity to evolve into drug resistant strains that threaten health care. To help tackle the problem, scientists in China have begun a pilot study examining biomarkers exhaled by patients. The team’s goal is to develop an efficient (fast, accurate, painless and affordable) test that will assist doctors in prescribing antibiotics only when the treatment is absolutely necessary.
8th June 2016

Device can absorb drugs after targeting tumors

Device can absorb drugs after targeting tumors
Doctors have a powerful arsenal of cancer-fighting chemotherapy drugs to choose from, though a key challenge is to better target these drugs to kill tumors while limiting their potentially harmful side effects. Now, researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) are helping to develop and test materials for a device that can be inserted via a tiny tube into a vein and soak up most of these drugs like a sponge.
7th June 2016

Model offers therapeutic target for pancreatic cancer

Model offers therapeutic target for pancreatic cancer
In a new study, published in Nature, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an innovative model that not only allowed them to track drug resistance in vivo, but also revealed a therapeutic target, which early testing suggests could provide a strategy to arrest pancreatic cancer growth.
6th June 2016

Bioactive macrocycle can be tailored for drug design

Bioactive macrocycle can be tailored for drug design
Researchers from Cornell University have devised a peptidomimetic macrocyclic compound that is made from an acid-catalysed cascade reaction. Their macrocycles are tunable in their backbone, side-chain composition and sequence, and their overall structure. Using this structural versatility, Mintu Porel, Dana N. Thornlow, Ngoc N. Phan and Christopher A. Alabi designed a macrocycle that mimicked antimicrobial peptides and displayed antibacterial properties when tested with Gram-positive and Gram-negative bacteria.
27th May 2016


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