Treatment

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Partnership could enable personalised therapies in MS

Partnership could enable personalised therapies in MS
A large global new partnership called 'MultipleMS', coordinated by Karolinska Institute in Sweden, has been awarded 15 million euro from the European Commission in the Horizon2020 program to find novel and better treatments for Multiple Sclerosis (MS). In this project, 21 universities and companies from Europe and the USA will unite efforts to tailor the development and application of therapies to the individual MS patient.
6th January 2017

Technique switches key biomolecules on and off

Technique switches key biomolecules on and off
A technique that will allow scientists to determine the effects of turning on and off a set of molecules involved in almost every cellular pathway, determine their downstream effects, and uncover new drug targets has been developed by researchers at the University of Illinois at Chicago. The finding is reported in the Proceedings of the National Academy of Sciences. Protein kinases are enzymes involved in almost every biological process.
14th December 2016

Skin cells unite to heal wounds

Skin cells unite to heal wounds
Time may not heal all wounds, but a proprietary mix of peptides and gel developed by U of T Engineering researchers heals most. A team led by Professor Milica Radisic has demonstrated for the first time that their peptide-hydrogel biomaterial prompts skin cells to "crawl" toward one another, closing chronic, non-healing wounds often associated with diabetes, such as bed sores and foot ulcers.
14th December 2016


Bringing life-saving cell therapies to the masses

Bringing life-saving cell therapies to the masses
Doctors knew long before Owen Webb was born that they were racing against the clock to save his life. Tests had confirmed the developing child suffered from Krabbe disease, a genetic disorder that causes toxins to build up in the nervous system, progressively damaging the brain. Just days after he was delivered, a medical team at Duke University began Owen on nine days of chemotherapy. His body was then infused with stem cell-rich donor umbilical cord blood.
12th December 2016

The latest weapon against Diabetes

The latest weapon against Diabetes
Researchers led by ETH Professor Martin Fussenegger at the Department of Biosystems Science and Engineering (D-BSSE) in Basel have produced artificial beta cells using a straightforward engineering approach. These pancreatic cells can do everything that natural ones do: they measure the glucose concentration in the blood and produce enough insulin to effectively lower the blood sugar level. The ETH researchers presented their development in the latest edition of the journal Science.
9th December 2016

Visual stimulation may be latest treatment for Alzheimer’s

Visual stimulation may be latest treatment for Alzheimer’s
Using LED lights flickering at a specific frequency, MIT researchers have shown that they can substantially reduce the beta amyloid plaques seen in Alzheimer’s disease, in the visual cortex of mice. This treatment appears to work by inducing brain waves known as gamma oscillations, which the researchers discovered help the brain suppress beta amyloid production and invigorate cells responsible for destroying the plaques.
8th December 2016

A radiation-free approach to imaging molecules in the brain

A radiation-free approach to imaging molecules in the brain
Scientists hoping to get a glimpse of molecules that control brain activity have devised a probe that allows them to image these molecules without using any chemical or radioactive labels. Currently the gold standard approach to imaging molecules in the brain is to tag them with radioactive probes. However, these probes offer low resolution and they can’t easily be used to watch dynamic events, says Alan Jasanoff, an MIT professor of biological engineering and brain and cognitive sciences.
5th December 2016

Biomarker could help guide cancer therapy

Biomarker could help guide cancer therapy
MIT biologists have identified a biomarker that can reveal whether patients with a particularly aggressive type of breast cancer will be helped by paclitaxel (commercially known as Taxol), one of the drugs most commonly used to treat this cancer. The findings could offer doctors a new way to choose drugs for this type of breast cancer, known as triple-negative because it lacks the three most common breast cancer markers: estrogen receptor, progesterone receptor, and Her2 protein.
22nd November 2016

Supercomputer simulations help fight antibiotic resistance

Supercomputer simulations help fight antibiotic resistance
Supercomputer simulations at the Department of Energy's Oak Ridge National Laboratory have played a key role in discovering a new class of drug candidates that hold promise to combat antibiotic resistance. In a study led by the University of Oklahoma with ORNL, the University of Tennessee and Saint Louis University, lab experiments were combined with supercomputer modeling to identify molecules that boost antibiotics' effect on disease-causing bacteria.
18th November 2016

Smart insulin-pen cap enables dosage data tracking

Smart insulin-pen cap enables dosage data tracking
MIT spinout Common Sensing aims to solve the nation’s diabetes-management issues by going digital. The startup’s smart insulin-pen cap logs insulin intake data on an app and in the cloud, to help patients better manage their regimen. Moreover, the cap gives doctors a detailed view into patients’ insulin habits and how they affect blood-glucose levels, for more targeted care. Invented by co-founders James White ’10, SM ’12 and Richard Whalley ’10, the Gocap is now going through clinical studies to test its viability.
17th November 2016


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