Nanomedicine

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DNA nanopackages help reveal how neurons work

DNA nanopackages help reveal how neurons work
A team of scientists from the University of Chicago designed a way to use microscopic capsules made out of DNA to deliver a payload of tiny molecules directly into a cell. The technique, detailed in Nature Nanotechnology, gives scientists an opportunity to understand certain interactions among cells that have previously been hard to track. “It’s really a molecular platform,” said Yamuna Krishnan, professor in chemistry and co-author of the study.
11th September 2017

Nanoparticles make targeted gene therapy possible

Nanoparticles make targeted gene therapy possible
Scientists at the Fred Hutchinson Cancer Research Center in Seattle, Washington have developed a nanoparticle messenger RNA (mRNA) delivery system to temporarily change gene expression in treated cells. Growing specific cell types in a lab and then administering them to patients is the goal of cell therapies, and these types of treatments are coming closer to reality for a variety of diseases.
5th September 2017

Drug loaded nanoparticles have potential to treat obesity

Drug loaded nanoparticles have potential to treat obesity
In a potential breakthrough for the treatment of obesity and diabetes, Purdue University scientists have found a way to deliver a drug directly to stored white fat cells to turn them into more easily burned brown fat cells. White adipose tissue, most associated with obesity, is a type of fat that collects in the body for long-term storage of energy. It’s possible humans evolved to store white fat to act as insulation and energy storage.
31st August 2017


Gold nanostars improve vaccine against cancer

Gold nanostars improve vaccine against cancer
By combining an FDA-approved cancer immunotherapy with an emerging tumour-roasting nanotechnology, Duke University researchers improved the efficacy of both therapies in a proof-of-concept study using mice. The potent combination also attacked satellite tumors and distant cancerous cells, completely curing two mice and effectively vaccinating one against the disease. The results appeared in Scientific Reports.
22nd August 2017

Medical device coating kills bacteria

Medical device coating kills bacteria
Researchers at KAUST (King Abdullah University of Science and Technology) in Saudi Arabia, not to be confused with KAIST (Korea Advanced Institute of Science and Technology), have developed a special nanoparticle coating that can be used to give the surfaces of medical devices antibacterial properties. The coating is made of gold nanoclusters containing lysozyme enzymes, an antibacterial agent, fused into a polymer matrix. The nanoparticles also contain kanamycin, an antibiotic.
18th July 2017

Manufacturing the future of nanomedicine

Manufacturing the future of nanomedicine
EU-funded RNA-based therapy targets the direct cause of some neurodegenerative diseases, not just their symptoms. The EU-funded B-SMART project, established to treat a range of neurodegenerative conditions, has taken a significant step towards this aim by selecting a platform to manufacture its nanomedicines. Precision NanoSystem's NanoAssemblr will use RNA-based therapeutics to stem disease producing proteins for conditions such as Parkinson’s, Alzheimer’s and Huntington’s.
2nd June 2017

Nanoparticle preparation with new Nano Pulveriser

Nanoparticle preparation with new Nano Pulveriser
The world of nanotechnology is already very impressive, however getting to an even smaller scale is increasingly important. For example, pharmaceutical companies who want their drugs to be faster acting on patients are considering nanoparticle formulation to improve the dissolution rate and solubility of their compounds.
26th April 2017

Nanowires accelerate development of neurological drugs

Nanowires accelerate development of neurological drugs
A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail. The nanowire technology could one day serve as a platform to screen drugs for neurological diseases and could enable researchers to better understand how single cells communicate in large neuronal networks.
19th April 2017

Preventing the formation of scar tissue around implants

Preventing the formation of scar tissue around implants
  Medical devices implanted in the body for drug delivery, sensing, or tissue regeneration usually come under fire from the host’s immune system. Defense cells work to isolate material they consider foreign to the body, building up a wall of dense scar tissue around the devices, which eventually become unable to perform their functions.
21st March 2017

A nanofibre matrix for healing

A nanofibre matrix for healing
A matrix made of gelatin nanofibers on a synthetic polymer microfiber mesh may provide a better way to culture large quantities of healthy human stem cells. Developed by a team of researchers led by Ken-ichiro Kamei of Kyoto University’s Institute for Integrated Cell-Material Sciences (iCeMS), the ‘fibre-on-fibre’ (FF) matrix improves on currently available stem cell culturing techniques.
16th March 2017


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