Nanomedicine

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How nanoparticles can eliminate bacteria more efficiently

How nanoparticles can eliminate bacteria more efficiently
Nanoparticle-based drugs have been considered an important contribution to personalised medicine for more than two decades. Potentially deliverable directly to tumors, infections and inflammations in a patient’s body, nanodrugs enable the combination of ideal dosing with precise targeting of the site of interest. To make this type of individualised treatment viable, two interconnected problems that can affect the efficiency of nanodrugs have to be surmounted.
22nd November 2017

Acoustofluidics separates exosomes from whole blood

Acoustofluidics separates exosomes from whole blood
A prototype device developed by an international team of engineers can sift exceedingly tiny particles from blood samples without having to send samples off to a lab. The device, which combines acoustic cell-sorting and microfluidic technologies, could be a boon to both scientific research and medical applications. The system is optimised to sort out “exosomes,” biological nanoparticles released from every type of cell in the body.
20th September 2017

DNA nanopackages help reveal how neurons work

DNA nanopackages help reveal how neurons work
A team of scientists from the University of Chicago designed a way to use microscopic capsules made out of DNA to deliver a payload of tiny molecules directly into a cell. The technique, detailed in Nature Nanotechnology, gives scientists an opportunity to understand certain interactions among cells that have previously been hard to track. “It’s really a molecular platform,” said Yamuna Krishnan, professor in chemistry and co-author of the study.
11th September 2017


Nanoparticles make targeted gene therapy possible

Nanoparticles make targeted gene therapy possible
Scientists at the Fred Hutchinson Cancer Research Center in Seattle, Washington have developed a nanoparticle messenger RNA (mRNA) delivery system to temporarily change gene expression in treated cells. Growing specific cell types in a lab and then administering them to patients is the goal of cell therapies, and these types of treatments are coming closer to reality for a variety of diseases.
5th September 2017

Drug loaded nanoparticles have potential to treat obesity

Drug loaded nanoparticles have potential to treat obesity
In a potential breakthrough for the treatment of obesity and diabetes, Purdue University scientists have found a way to deliver a drug directly to stored white fat cells to turn them into more easily burned brown fat cells. White adipose tissue, most associated with obesity, is a type of fat that collects in the body for long-term storage of energy. It’s possible humans evolved to store white fat to act as insulation and energy storage.
31st August 2017

Gold nanostars improve vaccine against cancer

Gold nanostars improve vaccine against cancer
By combining an FDA-approved cancer immunotherapy with an emerging tumour-roasting nanotechnology, Duke University researchers improved the efficacy of both therapies in a proof-of-concept study using mice. The potent combination also attacked satellite tumors and distant cancerous cells, completely curing two mice and effectively vaccinating one against the disease. The results appeared in Scientific Reports.
22nd August 2017

Medical device coating kills bacteria

Medical device coating kills bacteria
Researchers at KAUST (King Abdullah University of Science and Technology) in Saudi Arabia, not to be confused with KAIST (Korea Advanced Institute of Science and Technology), have developed a special nanoparticle coating that can be used to give the surfaces of medical devices antibacterial properties. The coating is made of gold nanoclusters containing lysozyme enzymes, an antibacterial agent, fused into a polymer matrix. The nanoparticles also contain kanamycin, an antibiotic.
18th July 2017

Manufacturing the future of nanomedicine

Manufacturing the future of nanomedicine
EU-funded RNA-based therapy targets the direct cause of some neurodegenerative diseases, not just their symptoms. The EU-funded B-SMART project, established to treat a range of neurodegenerative conditions, has taken a significant step towards this aim by selecting a platform to manufacture its nanomedicines. Precision NanoSystem's NanoAssemblr will use RNA-based therapeutics to stem disease producing proteins for conditions such as Parkinson’s, Alzheimer’s and Huntington’s.
2nd June 2017

Nanoparticle preparation with new Nano Pulveriser

Nanoparticle preparation with new Nano Pulveriser
The world of nanotechnology is already very impressive, however getting to an even smaller scale is increasingly important. For example, pharmaceutical companies who want their drugs to be faster acting on patients are considering nanoparticle formulation to improve the dissolution rate and solubility of their compounds.
26th April 2017

Nanowires accelerate development of neurological drugs

Nanowires accelerate development of neurological drugs
A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail. The nanowire technology could one day serve as a platform to screen drugs for neurological diseases and could enable researchers to better understand how single cells communicate in large neuronal networks.
19th April 2017


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